New sights of spleen-preserving versus splenectomy in distal pancreatectomy for pancreatic neuroendocrine tumors: a systematic review and meta-analysis - Takeaway - DentalSpire

New sights of spleen-preserving versus splenectomy in distal pancreatectomy for pancreatic neuroendocrine tumors: a systematic review and meta-analysis

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  • 1

    This study compares splenic-preserving distal pancreatectomy (SPDP) and distal pancreatectomy with splenectomy (DPS) for pancreatic neuroendocrine tumors (pNETs).

  • 2

    SPDP resulted in less intraoperative blood loss, shorter operative time, and fewer postoperative major complications compared to DPS in pNET patients.

  • 3

    The analysis included 457 patients, with 226 undergoing SPDP and 231 undergoing DPS, primarily involving well-differentiated G1/G2 tumors.

  • 4

    SPDP demonstrated a shorter hospital stay and lower transfusion rates, suggesting it may reduce surgical risks for selected pNET patients.

  • 5

    Further high-quality studies are needed to refine patient selection criteria and evaluate long-term outcomes of SPDP in managing pNETs.

Original Source(s)

New sights of spleen-preserving versus splenectomy in distal pancreatectomy for pancreatic neuroendocrine tumors: a systematic review and meta-analysis

  • by Haonan Liu, Kongyuan Wei, Ruiqi Cao, Shiwei Yang, Fangzhou Wang, Shengzhan Zhang, Jiaoxing Wu, Zhengyuan Feng, Cancan Zhou, Shuai Wu, Liang Han, Zheng Wang, Qingyong Ma, Zheng Wu

  • April 16, 2026

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