Clinical Guidelines

Retinal AI Predicts Neonatal Lung Disease

  • March 16, 2026

  • 4 min

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Deep learning models utilizing retinal images from routine retinopathy of prematurity (ROP) screenings have shown promise in predicting bronchopulmonary dysplasia and pulmonary hypertension in premature infants, as highlighted in a JAMA Ophthalmology study. Researchers analyzed fundus photographs from infants in the i-ROP study, finding that multimodal models combining both imaging data and demographic factors outperformed individual approaches. Despite limitations, such as small cohort sizes and potential confounding variables, the findings suggest retinal imaging may be a valuable tool for early identification of cardiopulmonary risks in neonatology.

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